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How to Take Ozempic: Step-by-Step Instructions

More and more people are considering Ozempic as a treatment option for type 2 diabetes, with Google searches for Ozempic rising by over 48% in the last year, and 284% since 2022 (according to Google Trends data). 

If you’re considering using Ozempic, however, it’s important that you follow the instructions provided by your healthcare professional. This can ensure your safety and help to minimise Ozempic side effects. 

We’re here to help. Here is our step-by-step guide on how to take Ozempic safely: 

1. Consult with Your Doctor

First of all, consult with your doctor or healthcare professional to discuss the best options that suit your preferences and requirements. 

Your doctor will explain what to expect from Ozempic, the potential benefits, as well as the potential risks and side effects. 

2. Understand the Medication

Before taking the medication, make sure you learn the important facts first. Learn how it works, what it does, and how it can help with weight loss and blood sugar control. 

Ozempic works by replicating the effects of the Glucagon-like peptide 1 (GLP-1) hormone, which naturally occurs in your body. This hormone essentially tells your brain that you are full and slows down digestion. 

Although this medication can lead to weight loss, it is not approved (officially) for weight loss alone in the UK. The guidance is clear - Ozempic is only suitable for adults with type 2 diabetes. Wegovy is the officially approved medication for weight loss that contains the same active ingredient, semaglutide. 

3. Acquire the Necessary Supplies

Now it’s time to get the right supplies. When you buy Ozempic, you should be provided with: 

  • Ozempic pen - containing a clear and colourless liquid, in doses of either 0.25 mg, 0.5 mg, or 1 mg per injection. 
  • New needles - one pen should contain four disposable needles
  • Pamphlet/ instructions for use - instructions, illustrations and prescribing information on how to prepare and inject the Ozempic pen 

Check you have exactly what you need, and then you can prepare for injection. 

4. Prepare for Injection

First of all, wash your hands thoroughly with soap and water, and then dry your hands before using the pen. Choose your injection site - you can opt for: 

  1. Stomach (2 inches away from belly button)
  2. Thigh (front or outer)
  3. Upper arm (at the back)

We recommend alternating your injection site (abdomen, thigh or upper arm) to prevent skin irritation and to ensure that the medication is absorbed efficiently. So, avoid using the same spot for each injection - even if you inject it in the same general area each time. 

5. Use the Ozempic Pen

Begin by removing the cap from the Ozempic pen, and then attach a new needle to the pen. When using a new pen for the first time, you need to test the pen. If this is the 2nd,3rd or 4th dose from the pen you can skip this step. The test shot is performed by dialling to the priming line with 2 dots just after the -0-. 

Hold the pen with the needle facing upwards and press the dose knob until the dose counter returns to -0-, lining up with the dose pointer and you will see some medication come out of the pen. If you do not, repeat the step until you have confirmed. This means that your pen is primed and ready to use.

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GIP & GLP-1 Medication

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Lose up to 15% in the first year
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Dose escalation available
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 6. Inject Ozempic

Follow these simple instructions to inject the pen into your chosen injection site: 

  • Hold the Ozempic pen at a 90-degree angle against the skin
  • Ensure it is firmly pressed against the injection site
  • Press the button to deliver the medication

The injection process may take a few seconds. Once complete, remove the pen from the skin.

7. Dispose of Used Needles

When you’ve finished with your dose of Ozempic, make sure you dispose of the needle safely. Place your used needle in a sharps container that will be provided by your health care provider - these containers are sealable, non-breakable and puncture-resistant. Check your local guidelines on how to dispose of the container - it may involve:

  • Dropping it off at a pharmacy
  • Utilising a ‘mail-back’ programme

DO NOT put the used needles in with your general waste, or flush them down the toilet. This can cause harm to the environment and to waste management workers. 

8. Follow Up with Your Doctor

To ensure your Ozempic journey remains safe, be sure to schedule regular appointments with your doctor. Your doctor will monitor your progress, check your HbA1C levels to see how Ozempic is affecting your blood sugar, and possibly adjust your dose as needed. 

Always let your doctor know if you begin taking any new medications whilst taking Ozempic. They can help watch out for any potential interactions, and ensure your treatment plan remains as suitable as possible. 

At Dr Frank’s Weight Loss Clinic, we have Mounjaro, Wegovy and Ozempic available for the management of Type 2 diabetes and weight loss. Our team of specialist clinicians, dieticians, coaches and nurses can offer you bespoke advice throughout your journey. We offer convenient monthly video check-ins to ensure that the process remains as streamlined as possible for you and that you get the best experience possible whilst taking GLP-1 medication. 

During your follow-ups with your specialist nurse, they will also monitor your side effects - learn more about these side effects below.

  

9. Be Aware of Common Side Effects

Make sure you’re aware of the potential side effects of Ozempic, such as diarrhoea or nausea. Here are some potential side effects to expect: 

  • Nausea
  • Diarrhoea
  • Headache
  • Fatigue

These side effects can be uncomfortable, but are short-lived and will usually subside as your body adjusts to the drug. 

10. Follow Dosage Instructions

Always follow your doctor’s dosage instructions when taking Ozempic. The starting dose for Ozempic is 0.25 mg once a week, and then after 4 weeks, your dose may be increased to 0.5 mg per week. It may then increase in another 4 weeks to a maximum of 1 mg once a week if the primary aim is glucose control and to 2.4 mg a week using Ozempic if the goal is weight loss. 

If you miss your dose, ensure you take it within the next five days. If five or more days have passed, wait for the next scheduled dose. 

Prof. Franklin Joseph, Endocrinologist
Professor Joseph is an experienced Consultant Physician in Endocrinology, Diabetes, and Obesity Management, specializing in Type 2 and Type 1 diabetes. He leads a clinical trials unit with top national recruitment for studies on obesity and diabetes therapies. He also chairs the Western Cheshire Diabetes Network and focuses on person-centered care for optimal patient outcomes.

Continue Your Weight Loss Discovery

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Susan lost 5 Stone in just 12 months

“For the first time, losing weight has been both easy and successful in my life.”

Cadi lost 3 Stone in just 12 months

“If you're aiming to lose weight or manage polycystic ovaries, go for this program. It's undoubtedly the best decision.”

Ethan lost 5 Stone in just 5 months

“I’ve never felt so comfortable in my own skin. It's a newfound sense of confidence and well-being that has positively impacted every aspect of my life.”

Dimitra lost 4 Stone in just 8 months

“I cannot recommend this programme enough; it truly works! It's the sole solution that has been effective after my long struggle.”

Lauren lost 5 Stone in just 8 months

“I would advise anyone considering this programme that it's a transformative experience. It has allowed me to embrace life and fully enjoy my twenties.”

Susan lost 5 Stone in just 12 months

“For the first time, losing weight has been both easy and successful in my life.”

Cadi lost 3 Stone in just 12 months

“If you're aiming to lose weight or manage polycystic ovaries, go for this program. It's undoubtedly the best decision.”

Ethan lost 5 Stone in just 5 months

“I’ve never felt so comfortable in my own skin. It's a newfound sense of confidence and well-being that has positively impacted every aspect of my life.”

Dimitra lost 4 Stone in just 8 months

“I cannot recommend this programme enough; it truly works! It's the sole solution that has been effective after my long struggle.”

Lauren lost 5 Stone in just 8 months

“I would advise anyone considering this programme that it's a transformative experience. It has allowed me to embrace life and fully enjoy my twenties.”